07/05/2014 - 12:00 - Sala Marie Curie

Post-transcriptional regulation by UNR: from dosage compensation to cancer progression

Scientific sessions, CRG Group Leader Seminars

Fatima Gebauer

Regulation of Protein Synthesis in Eukaryotes Group, Gene Regulation, Stem Cells and Cancer Programme, CRG

Short bio and talk summary

Fátima Gebauer received her PhD from the Autónoma University of Madrid, and worked as a postdoctoral fellow in the labs of Joel D Richter (UMAss, USA) and Matthias W Hentze (EMBL, Germany). In 2000, she obtained a staff scientist position at EMBL, and since 2002 she is group leader at the CRG.

Her lab focuses on the regulation of mRNA translation during embryonic development and cell homeostasis. In particular, she tries to understand the molecular mechanisms of translational control exerted by RNA-binding proteins (RBPs), the broader functions of RBPs at other steps of gene expression, and how RBP alterations contribute to cancer progression. Her talk will focus on one of these RBPs, the protein UNR. She will explain how molecular and genetics studies of UNR in Drosophila have led her lab to study cancer progression in humans.