21/05/2014 - 12:00 - Auditori PRBB

Human genetic diversity: adaptation and disease

Scientific sessions, CRG Group Leader Seminars

Elena Bosch

Evolutionary Biology Unit, UPF


Short biography

Elena Bosch started her doctoral research on population genomics of the North African populations in 1996, under the supervision of Jaume Bertranpetit. In February 2000, she moved to the UK, where she was appointed as Research Assistant at Leicester University to work on the human Y chromosome diversity and dynamics. In 2004, thanks to a “Ramón y Cajal” contract, she established her own research group at the Evolutionary Biology Unit at the UPF. In December 2008, she was granted tenure with an Associate Professor position that changed to Assistant Professor in February 2012.

Talk abstract

In the last years, her research work has focused on different aspects of the processes that affect genetic diversity in humans, including the population history of a number of different geographical human groups, the pattern of linkage disequilibrium around gene regions related to complex disease, and the imprint of natural selection. Her talk will summarize recent work on the functional validation of adaptive variants in two examples of recent human adaptation and will also cover her ongoing project on the role of rare variants in Parkinson’s disease.