15/06/2015 - 12:00 - Sala Marie Curie

Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung

Scientific sessions, PRBB CRG Conferences

Chris Siebel

Department of Discovery Oncology, Genentech Inc. South San Francisco, USA

Chris Siebel, from the Department of Discovery Oncology at Genentech Inc., South San Francisco, US, is aiming to understanding the role of Notch signaling in cancer, a highly conserved mechanism through which cells communicate with each other. He is using a variety of techniques, ranging from biochemical structure-function studies to genetic screens and in vivo models, with the goal of illuminating fundamental aspects of mammalian Notch biology and discovering new ways to treat cancer.

He has been invited by Anna Bigas (IMIM).