16/03/2016 - 12:00 - Auditori PRBB

How actomyosin contractile pulses shape tissues in development

Scientific sessions, CRG Group Leader Seminars

Jérôme Solon

Biomechanics of Morphogenesis Group, Cell and Developmental Biology Programme, CRG

Jérôme Solon's group is interested in describing the mechanisms at the origin of force generation, coordination and regulation in biological tissues. He focuses on Drosophila melanogaster embryogenesis and the dramatic tissue rearrangements that occur to shape the organism and form its organs. In particular, he studies Dorsal Closure (DC), a morphogenetic movement occurring at a late stage of Drosophila gastrulation. He aims to to link the mechanisms at the origin of cell movements with the activation of specific chemical network occurring during these movements, using an interdisciplinary approach, by combining expertise in Drosophila genetics and molecular biology with high-resolution live imaging, physical analysis and modeling, with the aim of building a quantitative description of the mechano-chemical properties of morphogenetic processes.