Mechanisms of genome maintenance during antigen receptor gene assembly

Ludovic Deriano, from the Institut Pasteur in Paris, France, aims to understand the mechanisms by which a lymphoid cell maintains the integrity of its DNA and prevents genomic instability and transformation. More precisely, he studies the DNA recombination processes that are part of B- and T-cell development and the mechanisms and pathways that lead to lymphoid cancers. He has been invited by José Yélamos (IMIM).