05/12/2012 - 12:00 - Sala 473.10

Function and evolution of alternative exon networks

Scientific sessions, PRBB CRG Conferences

Benjamin Blencowe

The Donnelly Centre, University of Toronto. Toronto, Canada

Ben Blencowe, from The Donnelly Centre of the University of Toronto in Toronto, Canada, is studying the mechanisms underlying the regulation of gene expression and how these mechanisms go awry in human diseases. In particular he aims to understand how alternative splicing is regulated and integrated with other layers of gene expression to control fundamental biological processes. He uses a wide range of approaches, from bioinformatics to focused molecular and biochemical methods, and has pioneered the development and application of methods for the genome-wide quantitative profiling of transcriptomes. These efforts have uncovered a remarkable landscape of new regulation that awaits further investigation. He has been invited by Juan Valcárcel (CRG).