12/04/2013 - 12:00 - Sala Marie Curie

The contribution of different regulation mechanisms in controlling metabolism

Scientific sessions, PRBB CRG Conferences

Uwe Sauer

Institute of Molecular Systems Biology, ETH Zurich. Zurich, Switzerland

Uwe Sauer, from the Institute of Molecular Systems Biology, ETH Zurich, in Switzerland, aims to identify and quantify the key regulatory mechanisms that control cellular metabolism in microbes and mammalian cells, using the model organisms E. coli and S. cerevisiae. His interdisciplinary team of biologists, engineers, and computer scientists are experts in high-throughput experimental technologies for quantitative metabolomics, 13C-based intracellular flux analysis, and dynamic GFP analysis in mini-scale cultivations. Different types of mathematical models are then used to quantitatively relate metabolomics, expression and proteomics data to the functional network output in terms of fluxes.

He has been invited by Eduard Sabidó (CRG).