Agenda
25/06/2012 - 12:00 - Sala Marie Curie

Cilia, ciliopathy proteins and brain morphogenesis


Scientific sessions, PRBB CRG Conferences

Sylvie Schneider- Maunoury

Vertebrate brain morphogenesis, INSERM; Developmental Biology Laboratory (LBD), CNRS, Université Pierre et Marie Curie. Paris, France



Schneider-Maunoury, from the Laboratory of Patterning and Morphogenesis of the Brain at the University Pierre and Marie Curie in Paris, France, is interested in the molecular and cellular mechanisms underlying brain morphogenesis in vertebrates, and in understanding how these mechanisms are perturbed in human diseases. To investigate these processes, she uses two complementary model organisms: the mouse and the zebrafish. She also studies the gene regulatory hierarchies involved in the early subdivision of the neural plate, the future central nervous system, during gastrulation. Schneider-Maunoury investigates the function of primary cilia in brain morphogenesis too. Specifically, she studies the Rpgrip1L gene, whose mutations have been identified in two human ciliopathies: Joubert and Meckel syndromes. She has been invited by Cristina Pujades (UPF).