Agenda
26/04/2013 - 12:00 - Sala Marie Curie

A whole can of worms: the effect of genome evolution on loss-of-function phenotypes in different nematodes


Scientific sessions, PRBB CRG Conferences

Andy Fraser

Banting and Best Department of Medical Research, Donnelly Centre, and Department of Molecular Genetics, University of Toronto. Toronto, Canada



Andy Fraser, from the Banting and Best Department of Medical Research, Donnelly Centre, and the Department of Molecular Genetics at the University of Toronto in Canada, uses the simple nematode worm C. elegans to address questions such as the effect of inherited mutations on our phenotype, how two independent mutations will combine, or how the same inherited mutation may affect different individuals. He combines RNAi-based screens with other cutting edge technologies to address genetics questions in four areas: genetic interactions in cancer pathways, evolution of gene function, predicting genetic interactions and transcriptomics. He has been invited by Ben Lehner (CRG).