15/10/2012 - 12:00 - Sala Marie Curie

Transcription complexes couple neural differentiation and neuronal subtype specification

Scientific sessions, PRBB CRG Conferences

Jane Johnson

Southwestern Medical Center at Dallas, The University of Texas. Dallas, USA

Johnson, from the Southwestern Medical Center at the University of Texas, Dallas, USA, is focused on vertebrate nervous system development during the transition from proliferating neural stem cells to differentiating neurons and glia. She uses the bHLH family of transcription factors to probe the molecular mechanisms controlling the balance of neural progenitor cell maintenance and differentiation, and the generation of neuronal diversity. Her lab utilises mouse models and overexpression in chick neural tube to probe the function of the bHLH factors, mechanisms of action of the bHLH factors, and the identity and fates of progenitors expressing each factor. She has been invited by Fernando Giráldez (UPF).