04/04/2014 - 12:00 - Sala Marie Curie

Investigating the relationship between geno-and phenotypic variation using regulatory genomics: A human and a Drosophila tale

Scientific sessions, PRBB CRG Conferences

Bart Deplancke

Laboratory of Systems Biology and Genetics, Institute of Bioengineering, École Polytechnique Fédérale de Lausanne. Lausanne, Switzerland

Bart Deplancke, from the Laboratory of Systems Biology and Genetics (LSBG) at the Institute of Bioengineering (IBI) in Lausanne, Switzerland, aims to unravel the metazoan gene regulatory code and to examine how variations in this code affect molecular and organismal diversity. He uses Drosophila melanogaster, to study the impact of genomic and molecular variation on gut immunity and aging; mouse, to study mesenchymal stem cell function and differentiation with a specific focus on the regulation of white and brown fat cell differentiation; and humans, linking genomic to regulatory variation. He is also actively pursuing the development of new research tools or pipelines that enable a better characterization of gene regulatory networks.

He has been invited by Kiana Toufighi (CRG).