News
12/6/2015

IBE (CSIC-UPF): IBE scientists study the human genome diversity of Sudan and neighboring countries

IBE (CSIC-UPF): IBE scientists study the human genome diversity of Sudan and neighboring countries


News from IBE (CSIC-UPF)


In this paper IBE researchers studied the human genome diversity of Sudan and neighboring countries in East Africa: South Sudan and Ethiopia. The scientists, leaded by Jaume Bertranpetit, found a common origin for most Nilo-Saharan speaking groups that differentiates them from other Sudanese or sub-Saharan populations, with a new, specific genetic component not present in other African populations. The study, published in Scientific Reports, a journal from the Nature Publishing Group, analized saliva samples that were collected from 500 individuals belonging to nine east African populations based on self-reported ethnicity.

Moreover, Bertranpetit and colleagues also found low genetic distances between these populations in genes important for anti-malarial and anti-bacterial host defence, indicating similar selective pressures on these genes and stressing the importance of considering functional pathways to understand the evolutionary history of populations.

Reference:
Dobon B, Hassan HY, Laayouni H, Luisi P, Ricaño-Ponce I, Zhernakova A, Wijmenga C, Tahir H, Comas D, Netea MG, and Bertranpetit J (2015). The genetics of East African populations: a Nilo-Saharan component in the African genetic landscape. Scientific Reports

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