News
24/7/2015

IMIM: Localized the brain mechanisms of the formation of fear

IMIM: Localized the brain mechanisms of the formation of fear


News from IMIM


Miguel Ángel Fullana, researcher at the Anxiety Unit of the Institute of Neuropsychiatry and Addictions of the Health Parc MAR and the Hospital del Mar Institute of Medical Research (IMIM), has coordinated the most comprehensive meta-analysis conducted so far on the neural basis of learning fear in humans. The study, published in the journal Molecular Psychiatry, analyzed the studies performed to date measuring brain activity during fear conditioning using functional magnetic resonance imaging (fMRI). The results show that in this process robustly activates a set of brain regions that constitute the "fear network".

The results of this work, which has involved national  (J. Raduà, C. Soriano-Mas, N. Cardoner, A. Avila-Parcet) and international researchers (B. Harrison, B.Vervliet) help understanding the transition between normal and pathological fear and in the long term, optimize the pathophysiological models to address anxiety disorders.

More information:
IMIM news (in Spanish)

Reference:
Fullana MA, Harrison BJ, Soriano-Mas C, Vervliet B, Cardoner N, Àvila-Parcet A, Rauda J. Neural signatures of human fear conditioning: an up date dandextended meta-analysis of fMRI studies. Mol Psychiatr 2015. Doi:10.1038mp.2015.88