News from CRG
Maria Chatzou, PhD student at the Comparative Bioinformatics laboratory has been recently awarded the Big Data Talent Award 2016 in the category of best doctoral thesis. The purpose of her thesis titled “Large-scale comparative bioinformatics analyses“ was to explore the impact of large-scale data analysis on multiple sequence alignment and phylogenetic reconstruction, two of the most popular modeling methods in biology.
Her approach will shed light to the new medial and research trends leading to personalised and precision medicine, involving large-scale analyses based in genome sequencing and biological data. All these opportunities raise up also many important issues, the most pressing ones being reliability and reproducibility. Maria and colleagues have found instability, which may have important consequences for personalised medicine, owing to the growing importance of these methods in treatments relying on personalised genomics analyses. In her thesis Maria developed these issues and their consequences. She also introduced solutions developed by herself, in the form of a new generation of computational tools allowing efficient and reproducible computation of complex pipeline based analyses.
Davide Cirillo at the Gene Function and Evolution laboratory was also distingued finalist in the category of best doctoral thesis. His thesis "Prediction of protein and nucleic acid interactions" was focused in developing high-performance bioinformatic methods to quantitative measure and predict the nucleic acids and protein interactions.