News from CEXS-UPF and IMIM
The european project transQST has been implemented with a funding of 16 M€. The iniative aims to improve the understanding of adverse drug reactions and the use of systems modelling approaches to drug safety. The Integrative Biomedical Informatics Research Group, led by Laura Furlong and Ferran Sanz and belonging to the Research Programme on Biomedical Informatics (GRIB), joint programme of UPF and IMIM, participates on this project coordinating the Work Package 4: Systems Modelling Tecnologies.
Funded by the Innovative Medicines Initiative 2 Joint Undertaking (IMI 2) the five-year project TransQST: Translational Quantitative Systems Toxicology, aims to develop novel computational approaches using the best available data from the public and private domains to address the problems of drug safety.
TransQT is a partnership between ten academic institutions, three Small and Medium-sized enterprises (SMEs) and eight pharmaceutical companies. One of the main focuses of the project are "off-target reactions" which cannot be predicted from the known pharmacological properties of the drug. The main organs of concern for such reactions are the liver, the kidney and the cardiovascular and gastrointestinal systems.