News
8/5/2020

First serological study among health care workers in Spain reveals lower-than-expected prevalence of SARS-CoV-2 infection

First serological study among health care workers in Spain reveals lower-than-expected prevalence of SARS-CoV-2 infection


News from ISGlobal


The Barcelona Institute for Global Health (ISGlobal) and the Hospital Clínic have coordinated the SEROCOV-1 serological study. This is the first study to measure the prevalence of antibodies against SARS-CoV-2 in a representative sample of health care workers in Spain.

The sample consisted of 578 staff members working at Hospital Clínic who had their antibodies measured against one of the SARS-CoV-2 proteins in blood samples. Specifically, IgA, IgM and IgG antibodies were quantified.

The study showed that while 39 of the 578 participants had been diagnosed with PCR prior to the trial, only 14 had an active infection (that is, positive PCR results) at the time of study kick-off. In addition, 54 participants had antibodies against the virus, which means a past or recent infection. However, out of these 54 people, almost the 40% were not diagnosed at the time of infection. Finally, the total of people who showed evidence of infection, either by PCR and/or by serology, was 65, that is, 11.2%.

This study has not been peer-reviewed and was posted as a preprint on the medRxiV server.

 

More information:
ISGlobal website