News from CREAL
Lifetime exposure to trihalomethanes (THM) has been associated with increased risk of bladder cancer. THMs are formed as by-products when chlorine is used to disinfect water for drinking. They are part of a group of chemicals known as disinfection by-products (DBPs) and THMs represent the chemical class of DBPs occurring at highest concentrations. They result from the reaction of chlorine and/or bromine with organic matter present in the water during treatment.
A research at the Centre for Research in Environmental Epidemiology (CREAL) lead by Dr. Lucas Salas, in the framework of a project coordinated by Dr. Cristina M. Villanueva, recently published in the American Journal of Epidemiology, has explored methods to analyze bladder cancer risk associated with the 4 main THMs (chloroform, bromodichloromethane, dibromochloromethane, and bromoform) as surrogates of DBP mixtures in a case control study conducted in Spain (1998–2001).
CREAL press release
Salas LA, Cantor KP, Tardón A, Serra C, Carrato A, García-Closas R, Rothman N, Malats N, Silverman D, Kogevinas M, Villanueva CM. Biological and Statistical Approaches for Modeling Exposure to Specific Trihalomethanes and Bladder Cancer Risk. Am J Epidemiol 2013 (in Press)