News
14/6/2013

IBE: European and Asian populations share the genetic risk of development of the most prevalent diseases

IBE: European and Asian populations share the genetic risk of development of the most prevalent diseases


The article was published in the journal PLOS Genetics


Researchers Urko Martínez-Marigorta and Arcadi Navarro, from the Institute of Evolutionary Biology (UPF-CSIC), have done the biggest comparative study to date on the genetic architecture of the most prevalent complex diseases in different human populations.

The results of the study, published today in PLOS Genetics, confirm that most of the common mutations that cause disease appeared before the separation of European and Asiatic populations. 

Some potential applications of the results of this study are sharing information across continents in order to increase the spectrum when designing new drugs, as well as alerting people with a higher risk to develop a certain disease.


Reference article:

Martinez-Marigorta U. and Navarro A. "High Trans-ethnic Replicability of GWAS Results Implies Common Causal Variants". PLOS Genetics. 13 June 2013. Doi pgen.1003566