News
4/10/2013

CRG: Functional genetic variation in humans. Comprehensive map published

CRG: Functional genetic variation in humans. Comprehensive map published


News from CRG


European scientists, led by researchers from the Faculty of Medicine of the University of Geneva (UNIGE) in the context of the GEUVADIS project, present a map that points to the genetic causes of differences between people. The study, published in Nature and Nature Biotechnology, offers the largest-ever dataset linking human genomes to gene activity at the level of RNA.

CRG scientists Xavier Estivill and Roderic Guigó lead the Spanish contribution to this study. Their lab members Marc Friedlander, Michael Sammeth, Pedro Ferreira and Ester Lizano prepared sequencing libraries and performed the bioinformatics analysis of the RNA data. This included a special pipeline of analysis for micro RNAs, which have a key role in regulating the expression of most genes. The scientific project manager for GEUVADIS, Gabrielle Bertier, also at the CRG, implemented an efficient data exchange and communication between researchers.

More information:

CRG press release

References:

Nature article
Nature Biotechnology