News from IMIM
A team of doctors at the Hospital del Mar, as well as researchers IMIM researchers (Hospital del Mar Medical Research Institute) and the CIBER of Respiratory Diseases (CIBERES), led by Esther Barreiro, has found two promising biomarkers to diagnose and predict the evolution of lung cancer in patients with Chronic Obstructive Pulmonary Disease (COPD). The study, published in the journal Free Radical Biology and Medicine, is the first to describe the levels of oxidative stress and inflammation in the blood and upper respiratory tract, distant from the tumor site in patients with lung cancer.
The researchers compared the physiological variables, and clinical and biological characteristics of 52 patients with lung cancer, with and without chronic obstructive pulmonary disease (COPD). These data were compared with a control group of 21 people without cancer, half with COPD and half without.
IMIM press release (Spanish)
“Oxidative stress and inflammation in the normal airways and blood of patients with lung cancer and COPD” E.Barreiro, C.Fermoselle, M.Mateu-Jimenez, A.Sánchez-Font, L.Pijuan, J.Gea, V.Curull. Free Radic Biol Med 2013; 65: 859-871.