News from IBE (CSIC-UPF)
The combination of experimental and bioinformatic approaches have allowed researchers from the J. Gonzalez Lab at IBE to connect a previously identified putatively adaptive Transposable Element (TE) insertion to its relevant fitness effect. The analyzed TE, named Bari-Jheh, adds extra antioxidant response elements (AREs) to the upstream region of Juvenile Hormone Epoxy Hydrolase genes resulting in increased resistance to oxidative stress.
Moreover, researchers show that TEs other than Bari-Jheh could also be adding AREs to the upstream regions of other genes suggesting a more general role of TEs in oxidative stress response.
Guio, L. Barrón M. , González, J. The transposable element Bari-Jheh mediates oxidative stress response in Drosophila. J. Mol Ecol. 2014 Mar 14. doi: 10.1111/mec.12711. [Epub ahead of print]