News
11/4/2014

IBE (CSIC-UPF): Genetic association of gastric cancer with miRNA clusters: Results from the EPIC-EURGAST study

IBE (CSIC-UPF): Genetic association of gastric cancer with miRNA clusters: Results from the EPIC-EURGAST study


News from IBE (CSIC-UPF)


An extensive European collaboration work has described a previously unreported genetic association of gastric cancer with microRNA clusters in chromosomes 7 and X that include miR-25, miR-29, miR-93 and miR-106. These microRNAs have been identified as novel genetic susceptibility factors for gastric cancer (GC), thus supporting their role in gastric carcinogénesis. Yolanda Espinosa is the first author of this study published in the International Journal of Cancer.

The data suggest these miRNAs as novel genetic susceptibility factors for GC. The article is an output of the EPIC-EURGAST study and has involved researchers from 24th European Institutions. The European Commission "Europe Against Cancer" Programme substantially supported EPIC financially. Additionally, each centre receives local financial support.

More information:
IBE news

Reference:
Espinosa-Parrilla et al. Genetic association of gastric cancer with miRNA clusters including the cancer-related genes MIR29, MIR25, MIR93 and MIR106: Results from the EPIC-EURGAST study. Int. J. Cancer: 00, 00-00 (2014) VC 2014 UICC. DOI: 10.1002/ijc.28850