News from CREAL
Gas cooking may contribute to an increase in bronchial responsiveness, a characteristic of asthma related to the contraction of the small airways. According to CREAL researchers, gas cooking affect people with GSTM1 null genotype and this may reflect the oxidant effects on bronchi of exposure to nitrogen dioxide.
Manolis Kogevinas, codirector of CREAL, an ISGlobal research centre, said that “since increased bronchial responsiveness is a characteristic feature of asthma, the present findings may help in understanding why some individuals may present asthma-related symptoms when cooking with gas while others do not”.
This study included data from subjects participating in the ECRHS, an international multicentre cohort study designed to identify risk factors for asthma. In total, around 5,000 people from 19 centres of 14 countries were included in this study.
Amaral AF, Ramasamy A, Castro-Giner F, Minelli C, Accordini S, Sorheim IC, Pin I, Kogevinas M, Jogi R, Balding DJ, Norbäck D, Verlato G, Olivieri M, Probst-Hensch N, Janson C, Zock JP, Heinrich J, Jarvis D. Interaction between gas cooking and GSTM1 null genotype in bronchial responsiveness: results from the European Community Respiratory Health Survey. Thorax 2014: (in Press)