News
13/6/2014

CREAL: Night shift work affects levels and timing of melatonin production

CREAL: Night shift work affects levels and timing of melatonin production


News from CREAL


A study published in Cancer Epidemiology, Biomarkers and Prevention has been focused on circadian variation of melatonin, light exposure and diurnal preference in day and night shift workers of both sexes. This research, leaded by Manolis Kogevinas, researcher at CREAL, an ISGlobal research center, concludes that night shift work affects levels and timing of melatonin production and that may relate to future cancer risk for these workers.

117 workers (75 night and 42 day) of both sexes, aged 22-64 years, were recruited from four companies. Participants collected urine samples from all voids over 24 hours and wore a data logger continuously recording their light exposure. Socio-demographic, occupational, lifestyle and diurnal preference information were collected by interview. Urinary 6-sulfatoxymelatonin, the main melatonin metabolite, concentrations were measured.

More information:
CREAL website

Reference:
Circadian variation of melatonin, light exposure and diurnal preference in day and night shift workers of both sexes. Papantoniou K1, Pozo O, Espinosa A, Marcos J, Castaño-Vinyals G, Basagaña X, Calduch Ribas F, Mirabent J, Martín J, Carenys G, Reyes Martín C, Middleton B, Skene DJ, Kogevinas M. Cancer Epidemiol Biomarkers Prev. 2014 May 8.