News
4/7/2014

IBE (CSIC-UPF): Human genomic regions with very high levels of population variation identified through whole genome scan methods

IBE (CSIC-UPF): Human genomic regions with very high levels of population variation identified through whole genome scan methods


News from IBE (CSIC-UPF)


The study published in the Open Access journal Genome Biology is the first published genome scan for positive selection using indel and SNP data from the Phase I of the 1000 Genomes Project in 14 populations. More precisely, sites showing extreme levels of differentiation among populations were identified as having putatively evolved under adaptive selection. This study was led by researchers at the Sanger Center (UK) in collaboration with IBE researchers.

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Reference:
Colonna, V., Ayub, Q., Chen, Y., Pagani, L., Luisi, P., Pybus, M., Garrison, E., Xue, Y., Tyler-Smith, C. 2014. Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences. Genome Biology 15: R88.