18/07/2016 - 12:00 - Sala Marie Curie

EMT and MET in cell fate transitions

Sessions científiques, PRBB CRG Conferences

Duanqing Pei

Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences. Guangzhou, China

Pei, Director General at the Guangzhou Institutes of Biomedicine and Health, in Guangzhou, China, studies the structure and function of Oct4, Sox2, FoxD3, Essrb, and Nanog, and their interdependent relationship towards pluripotency. Based the understanding of these factors, the Pei lab was the first in China to create mouse iPSCs using a non-selective system, and then improved the process and disseminated the technology in China by providing resources and training workshops. Now, he continues to explore new ways to improve iPSC technologies, dissecting the reprogramming mechanisms driven by Oct4/Sox2/Klf4 or fewer factors, and employing iPSCs to model human diseases in vitro. He has been invited by Ángel Raya (CMRB).