News from ISGlobal
Children and adolescents exposed to high levels of traffic-related air pollution have a higher risk of developing asthma, according to a systematic review and large-scale analysis performed by researchers from the ISGlobal and the University of Leeds.
This study, published in Environment International, is the largest and most up-to-date review and analysis of current evidence of exposure to traffic-related air pollution (TRAP) and development of childhood asthma. The authors reviewed more than 4,000 articles published on the topic between 1999 and September 2016, and analysed the data from 41 epidemiological studies from the Netherlands, the USA, Canada, Germany, Norway, Sweden, England, France, Italy, Japan, China, Taiwan, and Korea, that met criteria for inclusion in the systematic review. Khreis and co-authors then combined data for over a million kids in meta-analyses, and showed that TRAP exposures increase the risk of childhood asthma development.
Haneen Khreis, lead author of the study, concludes that “according to the analysis we performed, combining data from multiple studies, we can now confirm that there is a positive association between TRAP exposures and development of childhood asthma”. In particular, the review looked at exposure to traffic-associated nitrogen dioxide, black carbon, and particulate matter (PM2.5 and PM10) during childhood, and the subsequent development of asthma. “Our analysis shows that the most robust effects were in association with black carbon exposures, a specific marker of traffic exhaust and a diesel-related pollutant, but more research is needed to draw definitive conclusions, including exploring the effects of non-exhaust pollutants”.
Haneen Khreis, Charlotte Kelly, James Tate, Roger Parslow, Karen Lucas, Mark Nieuwenhuijsen. Exposure to traffic-related air pollution and risk of development of childhood. A systematic review and meta-analysis. Environmental International. DOI: 10.13140/RG.2.2.13217.81760.