News from IBE (CSIC-UPF)
Sphaeroforma arctica, an ichthyosporean - a group of unicellular eukaryotes characterized by the presence of large, multinucleated cells- undergoes regular cycles. This is the main conclusion of a study conducted by IBE researchers and led by Andrej Ondracka.
In this research, published at the journal Current Biology, several techniques were employed -flow cytometry, electronic particle counter, quantitative microscopy with image analysis and simple mathematical simulations― to measure the number of nuclei and cell size during the growth cycle. Scientists found that as cells grow, the cycles of nuclear division occurred with remarkably precise timing, and that the duration of the cycles was independent of the size of the cell or the rate of cell growth. This shows that the process is regulated by a molecular “timer”, very much similar to early embryonic cell cycles in animals. – Carlos Sierra / PRBB
Ondracka, O.; Dudin, O.; Ruiz-Trillo, I. (2018) Decoupling of Nuclear Division Cycles and Cell Size during the Coenocytic Growth of the Ichthyosporean Sphaeroforma arctica Current Biology 28, 1964–1969
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