News from ISGlobal
The results of a study led by a team from the ISGlobal suggest that the risk of a child developing symptoms of attention deficit hyperactivity disorder (ADHD) may be modulated by the mother’s diet during pregnancy. The study, published in The Journal of Pediatrics, analysed samples of umbilical cord plasma to quantify the levels of omega-6 and omega-3 that reach the foetus . The statistical analysis showed a higher omega-6:omega-3 ratio to be associated with a higher risk of ADHD symptoms at seven years of age.
The authors studied data from 600 children living in four Spanish regions (Asturias, Basque Country, Catalonia and Valencia) who are participating in the INMA project.
The results showed that, at age seven years, the number of ADHD symptoms increased by 13% per each unit increase in the omega-6:omega-3 ratio in umbilical cord plasma.
"Although the association was not clinically significant, our findings are important at the level of the population as a whole", noted López-Vicente. “If a large proportion of the population is exposed to a high omega-6:omega-3 ratio, the distribution for ADHD symptom scores would likely move to the right and the prevalence of extreme values would increase, leading to a negative impact on the community’s health costs and productivity.”
Mónica López-Vicente, Núria Ribas Fitó, Natalia Vilor-Tejedor, Raquel Garcia-Esteban, Sílvia Fernández-Barrés, Payam Dadvand, Mario Murcia, Marisa Rebagliato, Jesús Ibarluzea, Aitana Lertxundi, Ana Fernández-Somoano, Adonina Tardón, M. Carmen López-Sabater, Dora Romaguera, Martine Vrijheid, Jordi Sunyer, Jordi Julvez. Prenatal omega-6:omega-3 ratio and attention deficit and hyperactivity disorder symptoms, The Journal of Pediatrics, 2019.