News from CRG
Scientists around the world have today published the results of the third phase of the Encyclopedia of DNA Elements (ENCODE) in Nature. The international consortium of approximately 500 scientists conducted around 6000 experiments to identify more than 900,000 candidate regulatory elements from the human genome and more than 300,000 from the mouse, which can be explored through a new online browser.
Roderic Guigó at the Centre for Genomic Regulation (CRG) details that cells in the human body can be classified into five major groups. The researchers created this new classification by monitoring the transcriptome (variety of gene transcripts) of primary cells from multiple organs. He says that "our work redefines, based on gene expression, the basic histological types in which tissues have been traditionally classified".